Monkeypox testing has been started in Alappuzha NIV in the state in the context that monkeypox was confirmed in the state. Test kits are delivered from NIV Pune and the tests are conducted following strict safety standards. If cases increase, more labs will be set up to confirm monkeypox.

Monkeypox is confirmed by the RTPCR test. Samples such as secretions from the patient's nose and throat, secretions from blisters, urine, and blood are sent to the lab through a cold chain system. R.T.P.C.R. Using technology, the genetic material of the virus, DNA. The disease is confirmed by detection.

Monkeypox requires two PCRs.  First, an RTPCR test is performed to detect the virus belonging to the pox group. Through this, it is possible to know if there is a virus belonging to the pox group. If the first test is positive, Monkeypox will then conduct a confirmatory test.